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Preheat oven to 350 degrees F. Spray a 9x9-inch baking dish with nonstick spray and line with parchment paper.
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Add the white chocolate chips and butter to a microwave safe bowl. Microwave for 20 seconds, stir, and then microwave for another 20 seconds. Stir until completely melted.
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Pour the chocolate mixture into a larger bowl. Add the sugars and whisk to combine. Whisk in the egg, vanilla, and milk.
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In a separate bowl, whisk together the flour, cake mix, and salt.
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Fold the dry ingredients into the wet. When the mixture is just about combined, add in the sprinkles. Fold to combine until no more flour is visible.
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Spread the batter into the prepared dish. Top with a little sprinkle of a few more sprinkles.
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Bake for 20 minutes until edges are just slightly golden. Let cook completely in the pan before removing and slicing into 12-16 squares.
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Once the cooled squares are ready to be served, make the buttercream frosting.
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Add the butter and 1/2 cup of powdered sugar to a stand mixer fitted with the whisk attachment. Mix on low to combine and then on high to cream the butter for two minutes. Mix in the vanilla and salt.
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Mix in 1/4 to 1/2 cup of powdered sugar at a time until it becomes stiff.
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Spoon dollops of frosting on top of each blondie and then top with more sprinkles.